Join the team that’s bringing IMMUNO-INGENUITY to life

Let’s reshape the future of treating and preventing cancer & infectious disease.

Today, Inovio is poised to be the leader in the research and development of new and exciting therapies in oncology and infectious diseases. We aspire to develop and deliver breakthrough treatment modalities in disease states where effective cures have remained elusive. That’s because immuno-ingenuity is part of our DNA, and a dynamic entrepreneurial spirit is at the core of who we are.

The technology is here, and our team is growing. Now is the time for revolutionizing the world of immunotherapies. Now is the time to join the Inovio team—where passionate people are making a difference with immuno-ingenuity and more.

Career opportunities

Inovio Pharmaceuticals, Inc. is currently welcoming qualified applications for the following career opportunities:

  • Position

    Location

  • Associate Scientist, Bioengineering

    Research and Development

    San Diego, CA

    Company Profile

    Inovio is a late-stage biotechnology company focused on the discovery, development, and commercialization of DNA immunotherapies that transform the treatment of cancer and infectious diseases. Inovio is taking immunotherapy to the next level in the fight against cancer and infectious diseases. Inovio has reported generating T cells in vivo in high quantity that are fully functional and whose killing capacity correlates with relevant clinical outcomes with a favorable safety profile. With an expanding portfolio of immune therapies, the company is advancing a growing preclinical and clinical stage product pipeline. Partners and collaborators include MedImmune, Regeneron, Roche/Genentech, ApolloBio Corporation, The Wistar Institute, University of Pennsylvania, Parker Institute for Cancer Immunotherapy, CEPI, DARPA, GeneOne Life Science, Plumbline Life Sciences, Drexel University, NIH, HIV Vaccines Trial Network, National Cancer Institute, U.S. Military HIV Research Program, and Laval University. For more information, visit www.inovio.com.

    Job summary

    The Bioengineering Associate Scientist works within the R&D drug delivery group supporting the design, prototyping, and testing of DNA delivery systems. This individual conducts a broad range of experimental studies under minimal supervision, ranging from in silico simulations to in vivo studies using prototype drug delivery devices in appropriate animal models. The Bioengineering Associate Scientist performs a variety of immunological assays, analyzes data, and presents results. This individual is capable of working independently, solving complex bioengineering problems, and coordinating efforts within a multidisciplinary team.

    Essential job functions and duties

    • Design and execute in vivo studies to test hypotheses using appropriate control and experimental groups.
    • Utilize CAD and FEA software to design and prototype DNA delivery devices.
    • Perform laboratory assays and analysis on biological samples
    • Present experimental results in departmental and/or company meetings
    • Other duties as assigned

    Minimum requirements

    • Bachelor’s or Master’s degree in bioengineering or a closely related field
    • Four to six years of research experience with a BS/BA or two to four with a MS/MA within an academic or industrial setting
    • Experience in general laboratory techniques
    • Familiarity with principles of engineering design and finite element analysis
    • Excellent written and verbal communication skills
    • Preferred requirements
    • Prior experience with in vivo studies
    • Understanding of principles of immunology and relevant assays such as ELISA and ELISPOT
    • Previous experience with analytical programs such as R or Python, as well as Microsoft Excel and GraphPad Prism (or equivalent).
    • Previous experience with SolidWorks and ANSYS (or similar) software packages

    Disclaimer

    Inovio Pharmaceuticals, Inc. is committed to a policy of equal employment opportunity. In keeping with our policy, Inovio will recruit, hire, train and promote into all job titles the most qualified individuals, without regard to race, color, creed, gender, religion, marital status, registered domestic partner status, age, national origin or ancestry, veteran status, physical or mental disability, medical condition including genetic characteristics, sexual orientation, or any other consideration made unlawful by federal, state, or local laws.

    A current US work authorization is required. The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed. Inovio offers an attractive benefits package and is an equal opportunity employer. 

    Apply
  • Senior Mechanical Engineer

    Engineering

    San Diego, CA

    Company Profile

    Inovio is a late-stage biotechnology company focused on the discovery, development, and commercialization of DNA immunotherapies that transform the treatment of cancer and infectious diseases. Inovio is taking immunotherapy to the next level in the fight against cancer and infectious diseases. Inovio has reported generating T cells in vivo in high quantity that are fully functional and whose killing capacity correlates with relevant clinical outcomes with a favorable safety profile. With an expanding portfolio of immune therapies, the company is advancing a growing preclinical and clinical stage product pipeline. Partners and collaborators include MedImmune, Regeneron, Roche/Genentech, ApolloBio Corporation, The Wistar Institute, University of Pennsylvania, Parker Institute for Cancer Immunotherapy, CEPI, DARPA, GeneOne Life Science, Plumbline Life Sciences, Drexel University, NIH, HIV Vaccines Trial Network, National Cancer Institute, U.S. Military HIV Research Program, and Laval University. For more information, visit www.inovio.com.

    Job summary

    The Senior Mechanical Engineer (SME) works within the engineering group supporting new device development pertaining to drug and electroporation delivery technology. The SME is responsible for development of drug delivery systems and integration with Inovio electroporation technology and related components.  The SME develops device concepts to meet performance requirements determined by business development and the technical team, demonstrates feasibility through analysis and testing, refines product designs to meet cost and contract manufacturing goals, and verifies and validates finished products against specifications.  The SME also supports ongoing contract manufacturing sustaining engineering efforts.  Design work must be documented and test results recorded conforming to 21 CFR 820.30 requirements for medical device design control.  The SME position requires a diverse set of engineering skills with the major focus on mechanical engineering.

    Essential job functions and duties

    • Perform hands-on design, building, assembling and de-bugging of device prototypes.
    • Interact with Electrical Engineers to assist with PCB layout and electronic packaging.
    • Analyze and test designs to ensure cost and manufacturing feasibility.
    • Verify and validate finished products to meet required specifications.
    • Find, establish and work with outside vendors to fabricate prototype components.
    • Write protocols and reports, conduct product and component testing, and document work.
    • Participate in testing of de novo delivery devices in vivo using a wide spectrum of animal models, evaluating the efficacy, ease of use and overall performance of the new designs.

    Minimum requirements

    • B.S. Degree in mechanical engineering or a related field; or an equivalent combination of education, training and/or experience from which comparable knowledge, skills and abilities have been attained.
    • Minimum 5 years of mechanical engineering, design and CAD experience in the medical or other regulated industry.
    • Fluent experience with CAD modeling using SolidWorks and/or Pro-E.
    • Drafting practices and standards with basic understanding of ANSI Y 14.5, Geometric Dimensioning & Tolerancing.
    • Prior experience with statistical software for analyzing data and reporting results.
    • Knowledge of FEA modeling, CFD a plus.  
    • Experienced user of Microsoft office suite (Word, Excel and PowerPoint).
    • Excellent written and oral communication skills.
    • Ability to perform in both a team environment and under self-direction.
    • Comfortable with in vivo studies and a vivarium setting.

    Disclaimer

    Inovio Pharmaceuticals, Inc. is committed to a policy of equal employment opportunity. In keeping with our policy, Inovio will recruit, hire, train and promote into all job titles the most qualified individuals, without regard to race, color, creed, gender, religion, marital status, registered domestic partner status, age, national origin or ancestry, veteran status, physical or mental disability, medical condition including genetic characteristics, sexual orientation, or any other consideration made unlawful by federal, state, or local laws.

    A current US work authorization is required. The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed. Inovio offers an attractive benefits package and is an equal opportunity employer. 

    Apply
  • Sr Clinical Scientist

    Clinical Operations

    Plymouth Meeting, PA

    Company Profile

    Inovio is a late-stage biotechnology company focused on the discovery, development, and commercialization of DNA immunotherapies that transform the treatment of cancer and infectious diseases. Inovio is taking immunotherapy to the next level in the fight against cancer and infectious diseases. Inovio has reported generating T cells in vivo in high quantity that are fully functional and whose killing capacity correlates with relevant clinical outcomes with a favorable safety profile. With an expanding portfolio of immune therapies, the company is advancing a growing preclinical and clinical stage product pipeline. Partners and collaborators include MedImmune, Regeneron, Roche/Genentech, ApolloBio Corporation, The Wistar Institute, University of Pennsylvania, the Parker Institute for Cancer Immunotherapy, CEPI, DARPA, GeneOne Life Science, Plumbline Life Sciences, Drexel University, NIH, HIV Vaccines Trial Network, National Cancer Institute, U.S. Military HIV Research Program, and Laval University. For more information, visit www.inovio.com.

    Job summary

    S/he accountable for the global execution of assigned clinical trials from study design, through execution, to study close out.  Duties also include oversight of clinical trial operations as performed by a CRO or other external consultants.  This role applies to internally sourced studies and studies out-sourced to Clinical Research Organizations (CROs) and the balance of direct leadership versus oversight will vary accordingly. Responsible for authoring clinical documents (e.g., protocol, ICF, pharmacy manual, lab manual, etc.) and delivering clinical trials conducted globally. S/he will play a critical role in ensuring that these trials are executed in a way that meets ICH, GCPs, and local requirements. S/he will help ensure these trials achieves maximum productivity, efficiency, and compliance to national, international and local standards. S/he will contribute and drive ongoing process improvement initiatives. 

    Essential job functions and duties

    Leads the cross-functional study team responsible for clinical study delivery and is the primary point of contact of leadership and oversight (as required) for the assigned study.

    Prepare and finalize project and study-related documents including: informed consent forms, clinical trial outlines, monitoring plans, synopses, protocols and amendments, IND annual updates and clinical summaries, as required.

    Oversees data quality including regular review of data metrics and listings, protocol deviations, eligibility violations, dosing deviations, and suspected serious non-compliance by sites.

    Leads the development of and oversees implementation of patient recruitment and retention strategies and acts on any deviations from plan.

    Escalates issues related to study conduct, quality, timelines or budget to operations lead and other stakeholders and develops and implements appropriate actions to address issues.

    Manages and oversees study close-out activities including but not limited to database lock, reconciliation of vendor contracts, budget, TMF, and study drug accountability.

    Ensures accurate budget management and scope changes for assigned studies.

    Manage project timelines and vendor performance to meet departmental and corporate goals.

    Oversees and ensures the CROs and Third Party Vendors are in alignment and are delivering per the scope of work

    Responsible for identification of innovative approaches to clinical study execution including global considerations and continuous improvement of CTM SOPs.

    Participate in clinical and department settings, including attending additional meetings as required, interacting in a positive and professional manner.

    Perform other duties as assigned.

    Minimum requirements

    Bachelor’s degree and minimum of 6 years relevant industry experience; advanced degree is a plus.

    Ability to understand and implement the strategic direction and guidance for respective clinical studies.

    Proactive and self-disciplined, ability to meet deadlines, effective use of time, and prioritization.

    Ability to build productive teams and collaborations.

    Experience in CRO selection and management, including drafting request for proposals (RFPs), bidding process, etc.

    Experience in managing infectious disease clinical trials (emerging infectious diseases preferred).

    Knowledge of FDA, ICH, GCPs, and regulatory requirements.

    Experience in global clinical trial operations including experience developing protocols and key study documents. 

    Ability to work within a team, including leadership skills.

    Ability to organize and prioritize multiple tasks.

    Excellent communication and interpersonal skills.

    Attention to detail, organization, and problem-solving skills.

    Technical proficiency in trial management systems and MS applications including (but not limited to) Project, PowerPoint, Word, Excel, IVRS/IWRS, EDC.

    Disclaimer

    Inovio Pharmaceuticals, Inc. is committed to a policy of equal employment opportunity. In keeping with our policy, Inovio will recruit, hire, train and promote into all job titles the most qualified individuals, without regard to race, color, creed, gender, religion, marital status, registered domestic partner status, age, national origin or ancestry, veteran status, physical or mental disability, medical condition including genetic characteristics, sexual orientation, or any other consideration made unlawful by federal, state, or local laws.

    A current US work authorization is required. The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed. Inovio offers an attractive benefits package and is an equal opportunity employer. 

    Apply
  • Sr Director, Commercial

    Commercial

    Plymouth Meeting, PA

    Inovio is taking immunotherapy to the next level in the fight against cancer and infectious diseases. We are the only immunotherapy company that has reported generating T cells in vivo in high quantity that are fully functional and whose killing capacity correlates with relevant clinical outcomes with a favorable safety profile. The company is advancing a growing clinical and preclinical stage product pipeline. Partners and collaborators include MedImmune, University of Pennsylvania, DARPA, GeneOne Life Science, Drexel University, NIH, HIV Vaccines Trial Network, National Cancer Institute, U.S. Military HIV Research Program, and University of Manitoba. For more information, visit www.inovio.com.

    Job summary

    The Commercial Senior Director/Director, HPV will have responsibility for: 1) developing and executing the commercial strategy for VGX-3100.  This Phase 3 immunotherapy has the potential to be the first non-surgical treatment for cervical, vulvar, and anal HSIL (high-grade squamous intraepitheal lesions), which are pre-cancerous lesions caused by persistent HPV infection and; 2) providing commercial support for all Oncology and Infectious Disease R&D and clinical stage programs.  This individual will work closely with functional leadership company-wide and external stakeholders, in a high-profile role that is both strategic and executional in nature.

    Essential job functions and duties

    Develop/execute the marketing strategy and launch readiness plan for VGX-3100 across three separate indications

    Create market development plan to drive awareness of the unmet needs in the treatment of HPV-related disease and prepare the market for acceptance of an innovative new treatment paradigm

    Develop/execute the market access and reimbursement strategy for VGX-3100, and provide oversight of HEOR and comparative effectiveness modeling to support reimbursement

    Lead cross-functional execution of the market development plan, including scientific platform development, advisory boards, KOL engagement, professional society and patient advocacy group engagement, message platform, medial education, scientific dissemination, and congress planning

    Develop distribution strategy and packaging requirements for VGX-3100, including both the DNA immunotherapy and proprietary delivery device

    Develop/execute a market research/analytical plan to inform the commercialization strategy for VGX-3100.  Apply customer insights to inform decision-making and identify revenue opportunities 

    Identify external vendors (e.g., market research, medical communications, etc) to work with Inovio as strategic partners.  Manage relationship / budget to maximize the return on these investments

    Propose, gain support for, and manage the VGX-3100 commercial budget

    Participate in development of HPV franchise life cycle strategy, including partnering with business development in identifying and pursuing growth opportunities

    Conduct financial modeling to set revenue expectations and develop demand forecasts for programs across all stages for development

    Minimum requirements

    Bachelor’s degree, MBA preferred

    7+ years of biotech or pharmaceutical marketing/commercial experience including new product launch and market access experience

    Knowledge of the HPV market and key segments, including thought leaders, professional societies, patients advocacy groups, providers, patients, payers, and policy-makers is a plus

    Knowledge of current oncology market and R&D trends is a plus

    Essential requirements

    Demonstrated ability to develop/execute disruptive marketing new product launch strategies

    Ability to develop effective solutions for projects associated with a highly innovative technology and in business circumstances where there is little precedent and few analogues

    Experience working with payers in the US and developing market access and reimbursement solutions

    Experience managing medical communications, including cross-functional development of scientific platforms, messaging, and medical education

    Experience working with KOLs and designing/executing advisory boards to inform both clinical development and medical education plans

    Strong strategic and analytical skills, including ability to identify trends and business opportunities and develop data-driven recommendations to inform decision-making

    Strong business acumen, with demonstrated ability to identify, address, and influence customer needs and behaviors

    Experience in forecasting, P&L development, and NPV modeling

    Demonstrated cross-functional leadership, particularly in facilitating a dialogue that addresses business questions with solutions

    Outstanding interpersonal, communication (verbal, written), and influencing skills with ability to align team around a plan and motivate action to execute on it

    Ability to be hands-on as well as strategic, with strong drive to achieve results in a fast-paced, entrepreneurial biotech environment

    Disclaimer

    Inovio Pharmaceuticals, Inc. is committed to a policy of equal employment opportunity. In keeping with our policy, Inovio will recruit, hire, train and promote into all job titles the most qualified individuals, without regard to race, color, creed, gender, religion, marital status, registered domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition including genetic characteristics, sexual orientation, or any other consideration made unlawful by federal, state, or local laws.

    A current US work authorization is required.  The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed. Inovio offers an attractive benefits package and is an equal opportunity employer. 

    Apply

Inovio Pharmaceuticals, Inc. is committed to a policy of equal employment opportunity. In keeping with our policy, Inovio will recruit, hire, train, and promote into all job titles the most qualified individuals, without regard to race, color, creed, protected veteran status or disability, gender, religion, marital status, registered domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, including genetic characteristics, sexual orientation, or any other consideration made unlawful by federal, state, or local laws.

Important notice to employment businesses/agencies:

Inovio does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Inovio’s Human Resources Department to obtain prior written authorization before referring any candidates to Inovio. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/agency and Inovio. In the absence of such written authorization being obtained, any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of Inovio. Inovio shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.