Biography

Philip D. Greenberg, Ph.D.

PHILIP D. GREENBERG has had a long-standing research career elucidating the principles that underlie T-cell recognition of viruses and cancer cells, determining why such responses often fail to eliminate the viral pathogen or cancer, and developing cellular and molecular approaches to manipulate cellular immunity to treat human viral and malignant diseases. His current research includes studies in transgenic mice to elucidate the requirements for inducing therapeutically effective T-cell responses to self-proteins that are overexpressed in tumors, development of genetically-modified mice to better model human immune responses to facilitate the development of vaccines for HIV and cancer, genetic modification of T cells to improve efficacy in adoptive therapy, and clinical trials for the treatment of leukemia with adoptive T-cell therapy.